Postdoctoral Training Opportunity
Drug/Xenobiotic Metabolism and Accelerator Mass Spectrometry
Lawrence Livermore National Laboratory
The Biosciences Division and Center for Accelerator Mass Spectrometry at the Lawrence Livermore National Laboratory (LLNL) has an exciting opportunity to work as part of an integrated multi-disciplinary team of biochemists, toxicologists, chemists and physicists to study regulatory and metabolic processes in eukaryotic cells using the technique of accelerator mass spectrometry (AMS). The position involves developing and applying methods for the quantitate analysis of metabolites and metabolic pathways in cells, animal models, and humans using radio-labeled precursors along with AMS analysis. The successful candidate will also work with computer scientists to incorporate such quantitative data into models to simulate metabolic and cellular processes. This position is funded as part of LLNL's NIH-funded National Resource for Biomedical Accelerator Mass Spectrometry (RR013461). The position will report to the project's Principal Investigator.
To be considered, candidates should hold a recent Ph.D in biochemistry, toxicology/pharmacology, cell biology or related field. A background and interest in intermediary or drug metabolism, pharmacokinetics and analytical chemistry is preferred. US citizenship and a willingness to work with animals, radioisotopes, and human samples is required.
LLNL is U.S. Dept of Energy National Laboratory located in Livermore California with a large and growing program in the development and application of AMS to biomedical problems. Ongoing research ranges from ion source development to elucidation of the molecular mechanisms of disease and xenobiotic and drug metabolism. LLNL is situated in the east San Francisco Bay Area and is close to a large metropolitan area, a vibrant biotechnology industry and many well known universities. It offers an excellent living and research environment.